Outcomes According to Presentation With Versus Without Cardiogenic Shock in Patients With Left Main Coronary Artery Stenosis and Acute Myocardial Infarction

Title
Outcomes According to Presentation With Versus Without Cardiogenic Shock in Patients With Left Main Coronary Artery Stenosis and Acute Myocardial Infarction
Author(s)
김영조김웅박종선강상욱[강상욱]김유민[김유민]박원종[박원종]이상희홍그루신동구정명호[정명호]채성철[채성철]허승호[허승호]성인환[성인환]홍택종[홍택종]채인호[채인호]조명찬[조명찬]장양수[장양수]윤정한[윤정한]승기배[승기배]박승정[박승정]
Keywords
TOTAL OCCLUSION; INTERVENTION; DISEASE; ANGIOPLASTY; MANAGEMENT; STENT
Issue Date
201207
Publisher
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
Citation
AMERICAN JOURNAL OF CARDIOLOGY, v.110, no.1, pp.36 - 39
Abstract
This study is aimed at evaluating 1-year clinical outcomes and their predictors in patients with unprotected left main coronary artery (ULMCA)-related acute myocardial infarction (AMI). In total 248 patients diagnosed with AMI involving the ULMCA as the culprit vessel and registered in the Korean Acute Myocardial Infarction database were enrolled in this study. Patients were divided according to the absence (shock-, n = 206) or presence (shock+, n = 42) of cardiogenic shock at initial presentation. Independent risk factors of in-hospital cardiac death associated with ULMCA-related AMI were elucidated by multivariate regression analysis. In-hospital mortality rates were 8.7% in the shock- group and 47.6% in the shock+ group (p = 0.001). During 1-year follow-up after discharge, major adverse cardiac events developed in 16.3% of patients in the shock- group and 18.2% of patients in the shock+ group (p = 0.828); cardiac death, MI, and ischemia-driven target vessel revascularization were similar between the 2 groups at 1 year. On multivariate analysis, initial shock presentation (odds ratio 8.9, confidence interval 4.1 to 19.2, p = 0.004) and left ventricular ejection fraction <30% (odds ratio 7.6, confidence interval 2.7 to 21.1, p = 0.001) were independent risk factors of in-hospital cardiac death associated with ULMCA-related AMI. In conclusion, almost 1/2 of patients with ULMCA-related AMI presenting with cardiogenic shock had a fatal in-hospital outcome compared to <10% of those without cardiogenic shock; however, clinical outcomes after survival of the in-hospital period were not different between these groups. (C) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:36-39)
URI
http://hdl.handle.net/YU.REPOSITORY/27671http://dx.doi.org/10.1016/j.amjcard.2012.02.044
ISSN
0002-9149
Appears in Collections:
의과대학 > 내과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE