The neural connectivity of the inferior olivary nucleus in the human brain: A diffusion tensor tractography study

Title
The neural connectivity of the inferior olivary nucleus in the human brain: A diffusion tensor tractography study
Author(s)
장성호권혁규장평훈[장평훈]
Keywords
DESCENDING CONNECTIONS; MOTOR CORTEX; WHITE-MATTER; IN-VIVO; CAT; STEM; ORGANIZATION; PROJECTIONS; CEREBELLUM; PATHWAYS
Issue Date
201208
Publisher
ELSEVIER IRELAND LTD
Citation
NEUROSCIENCE LETTERS, v.523, no.1, pp.67 - 70
Abstract
Objectives: Many animal studies have reported on the neural connectivity of the inferior olivary nucleus (ION). However, the neural connectivity of the ION has not been clearly elucidated in the human brain. In this study, the neural connectivity of the ION in the human brain was investigated by diffusion tensor imaging (DTI). Methods: Forty healthy subjects were recruited. DTIs were acquired using a sensitivity-encoding head coil at 1.5T. Connectivity was defined as the incidence of connection between the ION and regions of interest (ROIs) in the brain. Results: In these subjects, the ION showed higher connectivity to the reticular formation (100%), the posterior limb of internal capsule (100%), the red nucleus (93.75%), the cerebral peduncle of midbrain (91.25%), the primary motor cortex (86.25%), the primary somatosensory cortex (85%), the periaqueductal gray mater (81.25%), the globus pallid us (81.25%), the anterior limb of internal capsule (62.5%), the pontine basis (62.5%), and the posterior parietal cortex (60%). Conclusions: The ION shows high connectivity with motor function-related areas, such as, the posterior limb of internal capsule, the red nucleus, the cerebral peduncle of midbrain, the primary motor cortex, and the pontine basis. These results indicate that the ION is closely related to motor function in the human brain. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/27535http://dx.doi.org/10.1016/j.neulet.2012.06.043
ISSN
0304-3940
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE