Amino acids as chiral selectors in enantioresolution by liquid chromatography

Title
Amino acids as chiral selectors in enantioresolution by liquid chromatography
Author(s)
수치딕시Ravi Bhushan[Ravi Bhushan]
Keywords
THIN-LAYER-CHROMATOGRAPHY; LIGAND-EXCHANGE CHROMATOGRAPHY; ADRENERGIC BLOCKING-AGENTS; ENANTIOMERIC PURITY; DIRECT RESOLUTION; OPTICAL ISOMERS; IMPREGNATED TLC; CAPILLARY-ELECTROPHORESIS; 2-ARYLPROPIONIC ACIDS; COPPER(II) COMPLEXES
Issue Date
201208
Publisher
WILEY-BLACKWELL
Citation
BIOMEDICAL CHROMATOGRAPHY, v.26, no.8, pp.962 - 971
Abstract
Amino acids are unique in terms of their structural features and multidimensional uses. With their simple structures and the ready availability of both enantiomers, amino acids not only serve as a chiral pool for synthesis but also provide an inexpensive pool for resolution studies. There has been no attempt to review the application of amino acids as chiral selectors for chromatographic enantioresolution of pharmaceuticals and other compounds. The present paper deals with application of l-amino acids and complexes of l-amino acids with a metal ion, particularly Cu(II), as an impregnating reagent in thin-layer chromatography or as a chiral ligand exchange reagent or a chiral mobile phase additive in both thin-layer chromatography and high-performance liquid chromatography. Enantiomeric resolution of beta-blockers, nonsteroidal anti-inflammatories, amino acids (and their derivatives) and certain other compounds is discussed. Copyright (c) 2012 John Wiley & Sons, Ltd.
URI
http://hdl.handle.net/YU.REPOSITORY/27494http://dx.doi.org/10.1002/bmc.2773
ISSN
0269-3879
Appears in Collections:
중앙도서관 > rims journal
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE