Delayed neural degeneration following gamma knife radiosurgery in a patient with an arteriovenous malformation: A diffusion tensor imaging study

Title
Delayed neural degeneration following gamma knife radiosurgery in a patient with an arteriovenous malformation: A diffusion tensor imaging study
Author(s)
장성호여상석
Keywords
CORTICOSPINAL TRACT; STROKE PATIENTS; BRAIN; RECOVERY; SURGERY; INJURY; TRACTOGRAPHY; EDEMA
Issue Date
201209
Publisher
IOS PRESS
Citation
NEUROREHABILITATION, v.31, no.2, pp.131 - 135
Abstract
Gamma knife surgery (GKS) is a proven modality for the treatment of arteriovenous malformations (AVMs), but neural degeneration is a serious complication of GKS. In this study, we report on a patient who displayed delayed neural degeneration following GKR, using diffusion tensor imaging (DTI). A 43-year-old male patient was diagnosed with an intraventricular hemorrhage (IVH) due to rupture of an AVM in the right middle cerebellar peduncle, and exhibited cognitive impairment, quadriparesis, and ataxia after IVH onset. He underwent GKS 5 weeks after onset. Brain MRIs performed at 6 weeks, 7 months, and 21months post-onset revealed encephalomalactic lesions in the right pons, middle cerebellar peduncle, and medulla oblongata. DTI at 6 weeks post-onset suggested neural injuries of the right corticospinal tract (CST), right middle cerebellar peduncle (MCP), and right inferior cerebellar peduncle (ICP). DTI at 7 months suggested that the right CST and right ICP had recovered to some extent, which concurred with improved clinical manifestations. However, at 21 months, four neural tracts (right CST, right MCP, and both ICPs) appeared to have degenerated, which was in-line with aggravation of corresponding clinical manifestations. Experiences of this patient suggest DTI is a useful technique for the detection of neural degeneration after GKS.
URI
http://hdl.handle.net/YU.REPOSITORY/27304http://dx.doi.org/10.3233/NRE-2012-0780
ISSN
1053-8135
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE