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dc.contributor.author강민규ko
dc.contributor.author김성훈ko
dc.contributor.author예지원ko
dc.contributor.author김성규ko
dc.contributor.author최지훈ko
dc.contributor.author오세안ko
dc.date.accessioned2015-12-17T02:11:19Z-
dc.date.available2015-12-17T02:11:19Z-
dc.date.created2015-11-29-
dc.date.issued201209-
dc.identifier.citationRadiation oncology journal, v.30, no.3, pp.146 - 151-
dc.identifier.issn1229-8719-
dc.identifier.urihttp://hdl.handle.net/YU.REPOSITORY/27244-
dc.identifier.urihttp://dx.doi.org/10.3857/roj.2012.30.3.146-
dc.description.abstractPurpose: This treatment planning study was undertaken to evaluate the impact of beam angle configuration of intensitymodulated radiotherapy (IMRT) on the dose of the normal liver in hepatocellular carcinoma (HCC). Materials and Methods: The computed tomography datasets of 25 patients treated with IMRT for HCC were selected. Two IMRT plans using fi ve beams were made in each patient; beams with equidistance of 72o (Plan I), and beams with a 30o angle of separation entering the body near the tumor (Plan II). Both plans were generated using the same constraints in each patient. Conformity index (CI), homogeneity index (HI), gamma index, mean dose of the normal liver (Dmean_NL), Dmean_NL difference between the two plans, and percentage normal liver volumes receiving at least 10, 20, and 30 Gy (V10, V20, and V30) were evaluated and compared. Results: Dmean_NL, V10, and V20 were signifi cantly better for Plan II. The Dmean_NL was signifi cantly lower for peripheral (p =0.001) and central tumors (p = 0.034). Dmean_NL differences between the two plans increased in proportion to gross tumor volume to normal liver volume ratios (p = 0.002). CI, HI, and gamma indices were not signifi cantly different for the two plans. Conclusion: The IMRT plan based on beams with narrow separations reduced the irradiated dose of the normal liver, which would allow radiation dose escalation for HCC.-
dc.language영어-
dc.publisher대한방사선종양학회-
dc.subjectHepatocellular carcinoma-
dc.subjectIntensity modulated radiation therapy-
dc.subjectRadiation therapy-
dc.titleThe impact of beam angle confi guration of intensitymodulated radiotherapy in the hepatocellular carcinoma-
dc.typeArticle-
dc.identifier.kciidART001701995-
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의과대학 > 방사선종양학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
이과대학 > 물리학과 > Articles
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