Benefit of Percutaneous Coronary Intervention in Early Latecomers With Acute ST-Segment Elevation Myocardial Infarction

Title
Benefit of Percutaneous Coronary Intervention in Early Latecomers With Acute ST-Segment Elevation Myocardial Infarction
Author(s)
김영조정명호[정명호]안영근[안영근]채성철[채성철]홍택정[홍택정]성인환[성인환]조명찬[조명찬]배장호[배장호]승기백[승기백]박승정[박승정]심두선[심두선]
Keywords
COLLATERAL BLOOD-FLOW; PRIMARY ANGIOPLASTY; MECHANICAL REPERFUSION; PROPENSITY SCORE; ARTERY; BIAS; ASSOCIATION; OCCLUSION; SURVIVAL; THERAPY
Issue Date
201211
Publisher
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
Citation
AMERICAN JOURNAL OF CARDIOLOGY, v.110, no.9, pp.1275 - 1281
Abstract
The clinical benefit of percutaneous coronary intervention (PCI) is controversial in stable early latecomers with ST-segment elevation myocardial infarction (STEMI). We evaluated the efficacy of PCI in 2,344 stable patients with STEW. presenting 12 to 72 hours after symptom onset. Patients who had impaired hemodynamics or who had undergone fibrinolysis or immediate or urgent PCI were excluded. The patients were divided into the PCI group (n = 1,889) and medical treatment group (n = 455). The 12-month clinical outcome was compared between the 2 groups. After adjustment using propensity score stratification, the PCI group had lower mortality (3.1% vs 10.1%; hazard ratio 0.31; 95% confidence interval 0.20 to 0.47; p < 0.001) and a lower incidence of composite death/myocardial infarction (3.8% vs 11.2%; hazard ratio 0.36; 95% confidence interval 0.25 to 0.53; p < 0.001) at 12 months. The benefit of PCI was consistent across all subgroups, including patients presenting without chest pain. In conclusion, in stable patients with STEM! presenting 12 to 72 hours after symptom onset, PCI was associated with significant improvement in the 12-month clinical outcome. (C) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:1275-1281)
URI
http://hdl.handle.net/YU.REPOSITORY/27011http://dx.doi.org/10.1016/j.amjcard.2012.06.028
ISSN
0002-9149
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의과대학 > 내과학교실 > Articles
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