Novel single nucleotide polymorphisms of bovine SREBP1 gene is association with fatty acid composition and marbling score in commercial Korean cattle (Hanwoo)

Title
Novel single nucleotide polymorphisms of bovine SREBP1 gene is association with fatty acid composition and marbling score in commercial Korean cattle (Hanwoo)
Author(s)
이제영Yoonseok Lee[Yoonseok Lee]오동엽라부미여정수
Keywords
ELEMENT-BINDING PROTEIN-1; JAPANESE BLACK CATTLE; SUBCUTANEOUS ADIPOSE-TISSUE; CARCASS CHARACTERISTICS; MEAT QUALITY; BEEF-CATTLE; STEERS; GROWTH; IDENTIFICATION; TRAITS
Issue Date
201301
Publisher
SPRINGER
Citation
MOLECULAR BIOLOGY REPORTS, v.40, no.1, pp.247 - 254
Abstract
The sterol regulatory element binding factor 1 (SREBP1) gene plays an important role in the biosynthesis of fatty acids. The aim of this study was to investigate the association between SNPs within SREBP1 gene and fatty acid composition of muscle fat and marbling score in a commercial population of Korean cattle. Among 10 SNPs in dbSNP of bovine SREBP1 gene, we identified 7 polymorphic SNPs and 84-bp ins/del variation (SREBP1-INT5 SNP) in commercial Korean cattle (n = 513). The SREBP1-9 SNP showed a significant effect on marbling score, monounsaturated fatty acids and C18:1n-9 in the muscle fat of commercial Korean cattle. However, SREBP1-INT5 SNP showed no effect on any fatty acid composition. Therefore, two polymorphisms in SREBP1 may improve flavored beef and meat quality in commercial Korean cattle.
URI
http://hdl.handle.net/YU.REPOSITORY/26856http://dx.doi.org/10.1007/s11033-012-2055-4
ISSN
0301-4851
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이과대학 > 통계학과 > Articles
생명공학부 > 생명공학부 > Articles
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