Phosphoiodyns A and B, Unique Phosphorus-Containing Iodinated Polyacetylenes from a Korean Sponge Placospongia sp.

Title
Phosphoiodyns A and B, Unique Phosphorus-Containing Iodinated Polyacetylenes from a Korean Sponge Placospongia sp.
Author(s)
최혁재김희영[김희영]진정욱[진정욱]백경렬[백경렬]이태구[이태구]박성은[박성은]왕위홍[왕위홍]한동엽[한동엽]양인호[양인호]이지혜[이지혜]문보라[문보라]Merrick Ekins[Merrick Ekins]남상집[남상집]강헌중[강헌중]
Keywords
CALLYSPONGIA-TRUNCATA; NATURAL-PRODUCTS; ACID; BIOSYNTHESIS; FOSFOMYCIN
Issue Date
201301
Publisher
AMER CHEMICAL SOC
Citation
ORGANIC LETTERS, v.15, no.1, pp.100 - 103
Abstract
Two unprecedented phosphorus-containing iodinated polyacetylenes, phosphoiodyns A and B (1-2), were isolated from a Korean marine sponge Placospongia sp. Their structures were elucidated by spectroscopic data analysis. Phosphoiodyn A exhibited potent agonistic activity on human peroxisome proliferator-activated receptor delta (hPPAR delta) with an EC50 of 23.7 nM.
URI
http://hdl.handle.net/YU.REPOSITORY/26724http://dx.doi.org/10.1021/ol3031318
ISSN
1523-7060
Appears in Collections:
약학대학 > 약학부 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE