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dc.contributor.author손종근ko
dc.contributor.author정수양[정수양]ko
dc.contributor.authorBing Tian Zhao[Bing Tian Zhao]ko
dc.contributor.author문동철[문동철]ko
dc.contributor.author강종성[강종성]ko
dc.contributor.author이제현[이제현]ko
dc.contributor.author민병선[민병선]ko
dc.contributor.author우미희[우미희]ko
dc.date.accessioned2015-12-17T01:54:11Z-
dc.date.available2015-12-17T01:54:11Z-
dc.date.created2015-11-13-
dc.date.issued201303-
dc.identifier.citationNatural Product Sciences, v.19, no.1, pp.28 - 35-
dc.identifier.issn1226-3907-
dc.identifier.urihttp://hdl.handle.net/YU.REPOSITORY/26194-
dc.description.abstractIn this study, quantitative and pattern recognition analysis for the quality evaluation of Cinnamomi Ramulus and Cinnamomi Cortex using HPLC/UV was developed. For quantitative analysis, three major bioactive compounds were determined. The separation conditions employed for HPLC/UV were optimized using an ODS C18 column (250 �� 4.6 mm, 5 ��m) with gradient conditions of acetonitrile and water as the mobile phase, at a flow rate of 1.0 mL/min and a detection wavelength of 265 nm. This method was fully validated with respect to linearity, accuracy, precision, recovery, and robustness. The HPLC/UV method was applied successfully to the quantification of three major compounds in the extract of Cinnamomi Ramulus and Cinnamomi Cortex. The HPLC analytical method for pattern recognition analysis was validated by repeated analysis of thirty eight Cinnamomi Ramulus and thirty five Cinnamomi Cortex samples. The results indicate that the established HPLC/ UV method is suitable for quantitative analysis.-
dc.language영어-
dc.subjectacetonitrile-
dc.subjectbiological marker-
dc.subjectcinnamaldehyde-
dc.subjectcinnamic acid-
dc.subjectCinnamomum cassia extract-
dc.subjectcoumarin-
dc.subjectwater-
dc.subjectarticle-
dc.subjectcinnamon-
dc.subjectcontrolled study-
dc.subjectflow rate-
dc.subjectprocess development-
dc.subjectprocess optimization-
dc.subjectquality control-
dc.subjectquantitative analysis-
dc.subjectreversed phase high performance liquid chromatography-
dc.subjectseparation technique-
dc.subjectultraviolet radiation-
dc.titleQuantitative analysis of bioactive marker compounds from Cinnamomi Ramulus and Cinnamomi Cortex by HPLC-UV-
dc.typeArticle-
dc.identifier.scopusid2-s2.0-84883035108-
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