Micro-optical lens array for fluorescence detection in droplet-based microfluidics

Title
Micro-optical lens array for fluorescence detection in droplet-based microfluidics
Author(s)
임지석Philipp Gruner[Philipp Gruner]Jean-Christophe Baret[Jean-Christophe Baret]Manfred Konrad[Manfred Konrad]
Keywords
FABRICATION; SURFACTANTS; EMULSIONS; FLOW
Issue Date
201304
Publisher
ROYAL SOC CHEMISTRY
Citation
LAB ON A CHIP, v.13, no.8, pp.1472 - 1475
Abstract
We demonstrate the design and integration of droplet-based microfluidic devices with microoptical element arrays for enhanced detection of fluorescent signals. We show that the integration of microlenses and mirror surfaces in these devices results in an 8-fold increase in the fluorescence signal and in improved spatial resolution. Using an array of microlenses, massively parallel detection of droplets containing fluorescent dyes was achieved, leading to detection throughputs of about 2000 droplets per second and per lens, parallelized over 625 measurement points.
URI
http://hdl.handle.net/YU.REPOSITORY/26066http://dx.doi.org/10.1039/c3lc41329b
ISSN
1473-0197
Appears in Collections:
공과대학 > 기계공학부 > Articles
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