Evaluation of hybrid PET/CT gastrography in gastric cancer

Title
Evaluation of hybrid PET/CT gastrography in gastric cancer
Author(s)
조인호공은정정주혜천경아장병익김태년김상운송선교
Keywords
POSITRON-EMISSION-TOMOGRAPHY; LYMPH-NODE STATUS; F-18-FDG PET; CT
Issue Date
201305
Publisher
SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN
Citation
NUKLEARMEDIZIN-NUCLEAR MEDICINE, v.52, no.3, pp.107 - 112
Abstract
Aim: With the recent advances in multidetector-row CT, a fusion of functional PET with three dimensional (3D) CT gastrography may provide enhanced diagnostic capability and help surgeons during preoperative planning. The diagnostic value of hybrid PET/CT gastrography was compared with that of conventional PET/CT alone in gastric cancer staging. Patients, methods: Patients with gastric cancer (n = 101) confirmed by endoscopic biopsy specimens underwent conventional PET/CT and regional PET with contrast enhanced CT, followed by gastrectomy with lymphadenectomy at our institution from November 2007 to November 2008. These images were fused into a hybrid PET/CT gastrography using the cardiac IQ fusion software. Conventional PET/CT and hybrid PET/CT gastrography were evaluated for staging of gastric cancer. After gastrectomy, these were compared with pathologic reports respectively. Results: Gastric cancer was diagnosed as 50 early gastric cancer (EGC) and 51 advanced gastric cancer (AGC) on pathologic examination. In EGC, hybrid PET/CT gastrography and PET/CT identified 36 (72%) and 7 (14%) tumours, respectively. Hybrid PET/CT gastrography correctly delineated the subtype of 25 EGC. In AGC, all 51(100%) tumours were identified on the hybrid PET/CT gastrography compared to 39 (76.5%) tumours on PET/CT. Hybrid PET/CT gastrography correctly classified the morphology of 42 AGC using the Bormann classification. Additionally, depth of invasion was correctly presented in 38 of 51 AGC. Hybrid PET/CT gastrography for regional lymph node (LN) metastasis in the EGC and AGC showed the sensitivity of 75% and 83.9%, and specificity 90.5% and 55%, respectively. Conclusion: Hybrid PET/CT gastrography is the more intuitive and comprehensive method for the preoperative evaluation of gastric cancer than conventional PET/CT.
URI
http://hdl.handle.net/YU.REPOSITORY/25932http://dx.doi.org/10.3413/Nukmed-0504-12-05
ISSN
0029-5566
Appears in Collections:
의과대학 > 핵의학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
의과대학 > 내과학교실 > Articles
의과대학 > 성형외과학교실 > Articles
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