The iScore Predicts Functional Outcome in Korean Patients With Ischemic Stroke

Title
The iScore Predicts Functional Outcome in Korean Patients With Ischemic Stroke
Author(s)
이준박태환[박태환]Saposnik Gustavo[Saposnik Gustavo]배희준[배희준]박종무[박종무]이수주[이수주]이경복[이경복]최재철[최재철]이병철[이병철]윤병우[윤병우]
Keywords
PROGNOSTIC MODELS; VALIDATION; SCORE; SCALE
Issue Date
201305
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Citation
STROKE, v.44, no.5, pp.1440 - +
Abstract
Background and Purpose-Several stroke risk scores for prediction of functional outcome have been developed, but rarely validated in Asian populations. We assessed the validity of the iScore, recently developed from Canadian stroke population, in an Asian stroke population from Korea. Methods-We applied the iScore to 4061 eligible participants with acute ischemic stroke in the nationwide multicenter stroke registry in Korea. The main outcome was poor functional outcome defined as having a modified Rankin Scale 3 to 6 at 3 months after stroke onset. The secondary outcome was death at 3 months. C-statistics were calculated to assess performance of the iScore. Results-Poor functional outcome was found in 1496 patients (36.8%), whereas death at 3 months occurred in 294 patients (7.2%). C-statistics were 0.819 (95% confidence interval, 0.805-0.833) for poor functional outcome and 0.861 (95% confidence interval, 0.840-0.883) for death. Overall, there was a high correlation between observed and expected outcomes for poor functional outcome (Pearson correlation coefficient, r=0.990) and for death (r=0.969) according to risk score. Conclusions-The iScore reliably predicts poor functional outcome or death at 3 months after stroke in Korean patients. (Stroke. 2013;44:1440-1442.)
URI
http://hdl.handle.net/YU.REPOSITORY/25905http://dx.doi.org/10.1161/STROKEAHA.111.000748
ISSN
0039-2499
Appears in Collections:
의과대학 > 신경과학교실 > Articles
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