Environmental factors affecting indole production in Escherichia coli

Title
Environmental factors affecting indole production in Escherichia coli
Author(s)
이진태조무환한티힙이진형토마스우드[토마스우드]
Keywords
GENE-EXPRESSION; DNA MICROARRAY; EXTRACELLULAR SIGNAL; BIOFILM FORMATION; ANAEROBIC GROWTH; HEAT-SHOCK; IN-VITRO; TRYPTOPHANASE; STRESS; K-12
Issue Date
201103
Publisher
ELSEVIER SCIENCE BV
Citation
RESEARCH IN MICROBIOLOGY, v.162, no.2, pp.108 - 116
Abstract
A variety of both Gram-positive and Gram-negative bacteria produce large quantities of indole as an intercellular signal in microbial communities. Biosynthesis of indole is well-studied, and while carbon sources and amino acids are important environmental cues for indole production in Escherichia coli, other environmental factors affecting indole production for this strain are less clear. This study demonstrates that the environmental cue pH is an important factor for indole production that further controls biofilm formation of E. coli. Moreover, E. coli produced a higher level of extracellular indole in the presence of the antibiotics ampicillin and kanamycin, and the increased indole enhanced cell survival during antibiotic stress. Additionally, we found here that temperature is another important factor for indole production; E. colt produces and accumulates a large amount of indole at 50 degrees C, even at low cell densities. Overall, our results suggest that indole is a stable biological compound, and E. colt may utilize indole to protect itself against other microorganisms. (C) 2010 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/25567http://dx.doi.org/10.1016/j.resmic.2010.11.005
ISSN
0923-2508
Appears in Collections:
공과대학 > 화학공학부 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE