Hospital Discharge Risk Score System for the Assessment of Clinical Outcomes in Patients With Acute Myocardial Infarction (Korea Acute Myocardial Infarction Registry [KAMIR] Score)

Title
Hospital Discharge Risk Score System for the Assessment of Clinical Outcomes in Patients With Acute Myocardial Infarction (Korea Acute Myocardial Infarction Registry [KAMIR] Score)
Author(s)
김영조김현국[김현국]정명호[정명호]안영근[안영근]김종현[김종현]채성철[채성철]허승호[허승호]성인환[성인환]홍택종[홍택종]최동훈[최동훈]조명찬[조명찬]김종진[김종진]승기배[승기배]정웅성[정웅성]장양수[장양수]라승운[라승운]배장호[배장호]조정관[조정관]박승정[박승정]
Keywords
ACUTE CORONARY SYNDROMES; CONGESTIVE-HEART-FAILURE; VENTRICULAR SYSTOLIC FUNCTION; BLOOD-GLUCOSE; ST-ELEVATION; STRATIFICATION; TRENDS; ASSOCIATION; SURVIVAL; CARE
Issue Date
201104
Publisher
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
Citation
AMERICAN JOURNAL OF CARDIOLOGY, v.107, no.7, pp.965 - 971
Abstract
Assessment of risk at time of discharge could be a useful tool for guiding postdischarge management. The aim of this study was to develop a novel and simple assessment tool for better hospital discharge risk stratification. The study included 3,997 hospital-discharged patients with acute myocardial infarction who were enrolled in the nationwide prospective Korea Acute Myocardial Infarction Registry-1 (KAMIR-1) from November 2005 through December 2006. The new risk score system was tested in 1,461 hospital-discharged patients who were admitted from January 2007 through January 2008 (KAMIR-2). The new risk score system was compared to the Global Registry of Acute Coronary Events (GRACE) postdischarge risk model during a 12-month clinical follow-up. During 1-year follow-up, all-cause death occurred in 228 patients (5.7%) and 81 patients (5.5%) in the development and validation cohorts, respectively. The new risk score (KAMIR score) was constructed using 6 independent variables related to the primary end point using a multivariable Cox regression analysis: age, Killip class, serum creatinine, no in-hospital percutaneous coronary intervention, left ventricular ejection fraction, and admission glucose based on multivariate-adjusted risk relation. The KAMIR score demonstrated significant differences in its predictive accuracy for 1-year mortality compared to the GRACE score for the developmental and validation cohorts. In conclusion, the KAMIR score for patients with acute myocardial infarction is a simpler and better risk scoring system than the GRACE hospital discharge risk model in prediction of 1-year mortality. (C) 2011 Elsevier Inc. All rights reserved. (Am J Cardiol 2011;107:965-971)
URI
http://hdl.handle.net/YU.REPOSITORY/25410http://dx.doi.org/10.1016/j.amjcard.2010.11.018
ISSN
0002-9149
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의과대학 > 내과학교실 > Articles
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