전경골 점액수종으로 진단된 그레이브스 병

Title
전경골 점액수종으로 진단된 그레이브스 병
Other Titles
A Case of Graves’ Disease Diagnosed by the Presenting Sign of Pretibial Myxedema
Author(s)
신동훈이효진[이효진]김영식[김영식]최종수김기홍
Keywords
Graves’ disease; Pretibial myxedema
Issue Date
201104
Publisher
대한피부과학회
Citation
대한피부과학회지, v.49, no.04, pp.353 - 356
Abstract
Pretibial myxedema (PTM) is a asymptomatic localized thickening of the pretibial skin due to deposition of acid mucopolysacharides (glycosaminoglycans). PTM, Graves’ ophthalmopathy (GO) and thyroid acropachy are the triad of classic extrathyroidal manifestations of Graves' disease. PTM usually follows the onset of GO, and PTM develops after the diagnosis and treatment of hyperthyroidism. We report here on a 51-year-old female who presented with painful, well demarcated hyperpigmented plaques with nonpitting edema on both lower legs. The histopathologic findings showed an increased accumulation of mucin throughout dermis. In our patient, PTM was the earliest manifestation and this led to the diagnosis of Graves' disease.
URI
http://hdl.handle.net/YU.REPOSITORY/25293
ISSN
0494-4739
Appears in Collections:
의과대학 > 피부과학교실 > Articles
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