Periventricular White Matter Injury by Primary Intraventricular Hemorrhage: A Diffusion Tensor Imaging Study

Title
Periventricular White Matter Injury by Primary Intraventricular Hemorrhage: A Diffusion Tensor Imaging Study
Author(s)
장성호여상석최병연장철훈정영진안상호변우목손수민
Keywords
SPONTANEOUS INTRACEREBRAL HEMORRHAGE; MENTAL-STATE-EXAMINATION; AXONAL INJURY; BRAIN; HYDROCEPHALUS; TRACTOGRAPHY; LEUKOMALACIA; ETIOLOGY; INFANTS; LESIONS
Issue Date
201110
Publisher
KARGER
Citation
EUROPEAN NEUROLOGY, v.66, no.4, pp.235 - 241
Abstract
Objectives: Intraventricular hemorrhage (IVH) in adult stroke patients is known to be an independent risk factor for poor functional outcome. Using diffusion tensor imaging (DTI), we attempted to investigate the effect of IVH on the white matter. Methods: We recruited 10 consecutive patients with IVH and 18 age-and sex-matched control subjects. Using a 1.5-T Philips Gyroscan Intera system, DTI data was acquired at an average of 84 days (range: 38-149) after IVH onset. We measured fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values at the fornix, corpus callosum (CC), corona radiata (CR), and posterior limb of the internal capsule (PL). In addition, integrity and fiber number were measured for the fornix. Results: DTI revealed disruption of the fornix in all patients. FA values showed a decrease in the fornix, CC, and CR; in contrast, the ADC value showed an increase in the CC, without changes in the fornix or CR. Fiber number of the fornix also decreased. However, no change was observed in the PL. Conclusions: We found periventricular white matter (fornix, CC, and CR) injury following IVH. We think that this result would be helpful in the establishment of management strategies for patients with IVH. Copyright (C) 2011 S. Karger AG, Basel
URI
http://hdl.handle.net/YU.REPOSITORY/24474http://dx.doi.org/10.1159/000330942
ISSN
0014-3022
Appears in Collections:
의과대학 > 재활의학교실 > Articles
의과대학 > 신경외과학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
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