Dentatorubrothalamic tract in human brain: diffusion tensor tractography study

Title
Dentatorubrothalamic tract in human brain: diffusion tensor tractography study
Author(s)
장성호권혁규홍지헌[홍지헌]홍철표[홍철표]이동훈[이동훈]안상호
Keywords
WHITE-MATTER; PROBABILISTIC TRACTOGRAPHY; CEREBELLAR PEDUNCLE; MOVEMENT-DISORDERS; MR TRACTOGRAPHY; HUMAN THALAMUS; 3 T; TRACKING; TREMOR; STEM
Issue Date
201110
Publisher
SPRINGER
Citation
NEURORADIOLOGY, v.53, no.10, pp.787 - 791
Abstract
The dentatorubrothalamic tract (DRTT) originates from the dentate nucleus in the cerebellum and terminates in the contralateral ventrolateral nucleus (VL) of the thalamus after decussating to the contralateral red nucleus. Identification of the DRTT is difficult due to the fact that it is a long, multisynaptic, neural tract crossing to the opposite hemisphere. In the current study, we attempted to identify the DRTT in the human brain using a probabilistic tractography technique of diffusion tensor imaging. Diffusion tensor imaging was performed at 1.5-T using a synergy-L sensitivity encoding head coil. DRTTs were obtained by selection of fibers passing through three regions of interest (the dentate nucleus, the superior cerebellar peduncle, and the contralateral red nucleus) from 41 healthy volunteers. Probabilistic mapping was obtained from the highest probabilistic location at 2.3 mm above the anterior commissure-posterior commissure level. DRTTs of all subjects, which originated from the dentate nucleus, ascended through the junction of the superior cerebellar peduncle and the contralateral red nucleus and then terminated at the VL nucleus of the thalamus. The highest probabilistic location for the DRTT at the thalamus was compatible with the location of the VL nucleus. We identified the DRTT in the human brain using probabilistic tractography. Our results could be useful in research on movement control.
URI
http://hdl.handle.net/YU.REPOSITORY/24450http://dx.doi.org/10.1007/s00234-011-0878-7
ISSN
0028-3940
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE