Acute Kidney Injury due to Sodium Bromate Intoxication: A Report of Two Cases

Title
Acute Kidney Injury due to Sodium Bromate Intoxication: A Report of Two Cases
Author(s)
도준영류동환장경애김석민[김석민]박종원윤경우
Keywords
Acute kidney injury; Sodium bromate
Issue Date
201112
Publisher
대한내과학회
Citation
The Korean Journal of Internal Medicine, v.26, no.4, pp.463 - 465
Abstract
Sodium bromate is a strong oxidant used as a neutralizing solution in hair permanents, as well as an auxiliary agent in printing and dyeing. Accidental or deliberate ingestion of bromate solution has rarely been reported in Korea. The clinical manifestations of bromate intoxication are vomiting, diarrhea, central nervous system symptoms, oliguric or non-oliguric acute kidney injury, hemolytic anemia, and deafness; most of these manifestations are reversible, with the exception of renal failure and deafness. Here, we report on two patients who demonstrated distinct clinical progressions. In the first case, a 16-year-old woman was successfully treated with hemodialysis and recovered renal function without hearing loss. However, in the second case, delayed hemodialysis resulted in persistent renal failure and hearing loss in a 77-yearold woman. This suggests that emergency therapeutic measures, including hemodialysis, should be taken as soon as possible, as the rapid removal of bromate may be essential to preventing severe intoxication and its sequelae.
URI
http://hdl.handle.net/YU.REPOSITORY/24139
ISSN
1226-3303
Appears in Collections:
의과대학 > 내과학교실 > Articles
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