8-아릴옥시카페인의 합성과 그 Topoisomerase II 저해활성
- 8-아릴옥시카페인의 합성과 그 Topoisomerase II 저해활성
- Other Titles
- Synthesis of 8-Aryloxycaffeines and Their Inhibitory Activities on Topoisomerase II
- 장영동; A. F. M 모튜어 라만[A. F. M 모튜어 라만]
- caffeine; 8-bromocaffeine; 8-aryloxycaffeine; Ullmann reaction; topoisomerase II
- Issue Date
- 약 학 회 지, v.55, no.6, pp.441 - 445
- A series of 8-(substituted)aryloxy- and 8-alkyloxy-caffenines were prepared from 8-bromocaffeine and (substituted)phenols as well as alkanols by Ullmann reaction and their inhibitory activities on topoisomerase II were evaluated.
A compound, 8-(quinolin-2-yl)oxycaffeine showed the strongest inhibitory activity against topoisomerase II.
- Appears in Collections:
- 약학대학 > 약학부 > Articles
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)