산겨릅나무 추출물의 간암세포의 증식억제 효과

Title
산겨릅나무 추출물의 간암세포의 증식억제 효과
Other Titles
Effect of Acer tegmentosum M. Extracts on Hepatocarcinoma Cell
Author(s)
방우석권하나[권하나]김주영박정륭전정례
Keywords
Acer tegmentosum M.; HepG2 hepatocarcinoma cell; MTT assay; anticancer
Issue Date
201112
Publisher
한국식품과학회
Citation
한국식품과학회지, v.43, no.6, pp.787 - 790
Abstract
The objective of this study was to investigate the anticancer effects of Acer tegmentosum M. extracts. HepG2hepatocarcinoma cells were treated with ethanol, chloroform, ethylacetate, butanol, aqueous fraction and hot water extract. The antiproliferative effect was evaluated by trypan blue exclusion, MTT-based viability assay and morphology. The trypan blue test showed that anticancer effect of the A. tegmentosum M. extracts on HepG2 cells increased gradually in proportion to the increasing concentration of the fractions. The butanol fraction showed the highest anticancer activity against HepG2cells (p<0.05). The MTT assay indicated that the growth inhibition by the butanol fraction was dose-dependent. These results suggest that A. tegmentosum M. has the potential to inhibit the growth of hepatocarcinoma cells.
URI
http://hdl.handle.net/YU.REPOSITORY/24066
ISSN
0367-6293
Appears in Collections:
생활과학대학 > 식품영양학과 > Articles
의과대학 > 해부학교실 > Articles
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