A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus

Title
A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
Author(s)
홍영훈윤대영[윤대영]오명진[오명진]이충기김현지[김현지]정용욱[정용욱]
Keywords
Nephrosis; lipoid; Lupus erythematosus; systemic; Mycophenolate mofetil
Issue Date
201112
Publisher
대한내과학회
Citation
The Korean Journal of Internal Medicine, v.26, no.4, pp.470 - 473
Abstract
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change disease and lupus nephritis. A 24-year-old woman diagnosed with SLE five years prior to presentation complained of a mild generalized edema. The urinalysis showed microscopic hematuria and proteinuria. The assessed amount of total proteinuria was 1,618 mg/24 hours. A renal biopsy demonstrated diffuse fusion of the foot processes of podocytes on electron microscopy. Mycophenolate mofetil was started in addition to the maintenance medications of prednisolone 10 mg/day and hydroxychloroquine 400 mg/day. After six months of treatment, the microscopic hematuria and proteinuria resolved, and the total urine protein decreased to 100 mg/24 hours.
URI
http://hdl.handle.net/YU.REPOSITORY/24045
ISSN
1226-3303
Appears in Collections:
의과대학 > 내과학교실 > Articles
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