Gender Differences in Clinical Features and In-hospital Outcomes in ST-segment Elevation Acute Myocardial Infarction: From the Korean Acute Myocardial Infarction Registry (KAMIR) Study

Title
Gender Differences in Clinical Features and In-hospital Outcomes in ST-segment Elevation Acute Myocardial Infarction: From the Korean Acute Myocardial Infarction Registry (KAMIR) Study
Author(s)
김영조박종선신동구정명호[정명호]안영근[안영근]정욱성[정욱성]승기배[승기배]김종진[김종진]조명찬[조명찬]장양수[장양수]박승정[박승정]성인환[성인환]채성철[채성철]허승호[허승호]최동훈[최동훈]홍택종[홍택종]
Issue Date
201008
Publisher
WILEY-BLACKWELL
Citation
CLINICAL CARDIOLOGY, v.33, no.8, pp.E1 - E6
Abstract
Background: Studies have suggested that women are biologically different and that female gender itself is independently associated with poor clinical outcome after an acute myocardial infarction (AMI). Hypothesis: We analyzed data from the Korean Acute Myocardial Infarction Registry (KAMIR) to assess gender differences in in-hospital outcomes post ST-segment elevation myocardial infarction (STEMI). Methods: Between November 2005 and July 2007, 4037 patients who were admitted with STEMI to 41 facilities were registered into the KAMIR database; patients admitted within 72 hours of symptom onset were selected and included in this study. Results: The proportion of patients who had reperfusion therapy within 12 hours from chest pain onset was lower in women. Women had higher rates of in-hospital mortality (8.6% vs 3.2%, P < .01), noncardiac death (1.5% vs 0.4%, P < .01), cardiac death (7.1% vs 2.8%, P < .01), and stroke (1.2% vs 0.5%, P < .05) than men. Multivariate logistic regression analysis identified age, previous angina, hypertension, a Killip class >= II, a left ventricular ejection fraction (LVEF) < 40%, and a thrombolysis in myocardial infarction flow (TIMI) grade <= 3 after angioplasty as independent risk factors for in-hospital death for all patients; however, female gender itself was not an independent risk factor. Conclusions: The results of this study show that although women have a higher in-hospital mortality than men, female gender itself is not an independent risk factor for in-hospital mortality.
URI
http://hdl.handle.net/YU.REPOSITORY/23889http://dx.doi.org/10.1002/clc.20557
ISSN
0160-9289
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의과대학 > 내과학교실 > Articles
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