국내 난치성 천식의 특징 - 파일럿 연구

Title
국내 난치성 천식의 특징 - 파일럿 연구
Other Titles
Characteristics of Difficult to Treat Asthma in Korea
Author(s)
이관호유광하[유광하]어수택[어수택]박용범[박용범]이양근[이양근]오연목[오연목]
Keywords
Asthma; Therapeutics; Korea; Adrenal Cortex Hormones; Comorbidity; Asthma; Therapeutics; Korea; Adrenal Cortex Hormones; Comorbidity
Issue Date
201009
Publisher
대한결핵및호흡기학회
Citation
Tuberculosis and Respiratory Diseases, v.69, no.5, pp.361 - 367
Abstract
Background: Difficult-to-treat asthma afflicts a small percentage of the asthma population. However, these patients remain refractory to treat, and account for 40% to 50% of the health costs of asthma treatment, incurring significant morbidity. We conducted a multi-center cross-sectional study to characterize difficult-to-treat asthma in Korea. Methods: Subjects with difficult-to-treat asthma and subjects with controlled asthma were recruited from 5 outpatient clinics of referral hospitals. We reviewed medical records of previous 6 months and obtained patient-reported questionnaires composed of treatment compliance, asthma control, and instruments for stress, anxiety, and depression. Results: We recruited 21 subjects with difficult-to-treat asthma and 110 subjects with controlled asthma into the study. The subjects with difficult-to-treat asthma were associated with longer treatment periods, more increased health care utilization, more medication (oral corticosteroids, number of medication), and more anxiety disorder compared to those of well-controlled asthmatics. There was no difference in age, gender, history of allergy, serum IgE, blood eosinophil count, or body mass index between the 2 groups. Conclusion: Difficult-to-treat asthma is characterized by increased health care utilization and more co-morbidity of anxiety.
URI
http://hdl.handle.net/YU.REPOSITORY/23548
ISSN
1738-3536
Appears in Collections:
의과대학 > 내과학교실 > Articles
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