구릿대 뿌리의 부위별 성분 비교

Title
구릿대 뿌리의 부위별 성분 비교
Other Titles
The Comparison of Constituents Distributed in the Root of Angelica dahurica
Author(s)
나민균윤의중[윤의중]유재국[유재국]진전성[진전성]이익수[이익수]민병선[민병선]정현주[정현주]서은경[서은경]배기환[배기환]
Keywords
Angelica dahurica; xanthotoxin; oxypeucedanin; imperatorin; HPLC
Issue Date
201009
Publisher
한국생약학회
Citation
생약학회지, v.41, no.3, pp.185 - 189
Abstract
In this study, we analyzed and quantified the amounts of bioactive phenolic constituents, xanthotoxin (1), oxypeucedanin (2), and imperatorin (3) in each part of the root of Angelica dahurica by HPLC, which validated by ICH guide lines comparing the linearity, intra day precision, inter-day precision. As a result, the amount of imperatorin 2.96% in the rootlet was two fold higher than that of the main root 1.32%. On the other hand, the amounts of xanthotoxin and oxypeucedanin in the rootlet showed similar to those of main root. In addition, the cortex of root is more plentiful of three consitituents (0.66%,0.53%, and 1.85%) than those of xylem (0.29%, 0.05%, and 0.07%). These results show that the rootlet and cortex contain a large amount of bioactive phenolic constituent including xanthotoxin, oxypeucedanin, and imperatorin than other parts of the root.
URI
http://hdl.handle.net/YU.REPOSITORY/23546
ISSN
0253-3073
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약학대학 > 약학부 > Articles
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