후천 면역 결핍 증후군 환자에서 발생한 Corynebacterium macginleyi 폐렴 1례

Title
후천 면역 결핍 증후군 환자에서 발생한 Corynebacterium macginleyi 폐렴 1례
Other Titles
Pneumonia Caused by Corynebacterium macginleyi in HIV-infected Patient
Author(s)
허지안
Keywords
Corynebacterium macginleyi; Pneumonia; Human immunodeficiency virus
Issue Date
201010
Publisher
대한감염학회
Citation
Infection and Chemotherapy, v.42, no.5, pp.319 - 322
Abstract
Corynebacterium macginleyi is usually isolated from the eye surfaces and causes ocular infections such as conjunctivitis, keratitis, and endophthalmitis. However,cases that describe C. macginleyi as the causative agent for significant and lifethreatening infections in immunocompromised patients are increasingly reported. Herein we report the first documented case of C. macginleyi pneumonia in a human immunodeficiency virus (HIV) patient. A 42-year-old homosexual man with HIV infection was hospitalized with a 1-month history of fever and dry cough. Chest radiograph revealed ill defined ground glass opacities in both lung fields. Methenamine silver stain of bronchoalveolar lavage fluid was negative. He showed clinical improvement after treatment with trimethoprim/sulfamethoxazole and prednisolone for three weeks, and was discharged. One month later, he presented with dyspnea and more progressive pulmonary infiltrations. Bronchial washing fluid culture yielded >100,000 colonies/mL of C. macginleyi , and he was given a 14-day course of antibiotic therapy with vancomycin, after which the patient fully recovered. This case suggest the importance of not overlooking the significance of positive cultures for C. macginleyi obtained from representative clinical samples in patients with signs and symptoms of bacterial infection.
URI
http://hdl.handle.net/YU.REPOSITORY/23450
ISSN
1598-8112
Appears in Collections:
의과대학 > 내과학교실 > Articles
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