Increase of Ceftazidime- and Fluoroquinolone-Resistant Klebsiella pneumoniae and Imipenem-Resistant Acinetobacter spp. in Korea: Analysis of KONSAR Study Data from 2005 and 2007

Title
Increase of Ceftazidime- and Fluoroquinolone-Resistant Klebsiella pneumoniae and Imipenem-Resistant Acinetobacter spp. in Korea: Analysis of KONSAR Study Data from 2005 and 2007
Author(s)
이채훈이경원[이경원]이미애[이미애]이종욱[이종욱]노경호[노경호]김선주[김선주]고은미[고은미]용동은[용동은]정윤섭[정윤섭]김진주[김진주]
Keywords
INTENSIVE-CARE UNITS; ANTIMICROBIAL RESISTANCE; BETA-LACTAMASE; STREPTOCOCCUS-PNEUMONIAE; ESCHERICHIA-COLI; HIGH PREVALENCE; NATIONWIDE SURVEILLANCE; ENTEROCOCCUS-FAECIUM; SOUTH-KOREA; SUSCEPTIBILITY
Issue Date
201011
Publisher
YONSEI UNIV COLL MEDICINE
Citation
YONSEI MEDICAL JOURNAL, v.51, no.6, pp.901 - 911
Abstract
Purpose: Antimicrobial resistance monitoring could be a useful source of information for treating and controlling nosocomial infections. We analyzed antimicrobial resistance data generated by Korean Hospitals and by a commercial laboratory in 2005 and 2007. Materials and Methods: Susceptibility data for 2005 and 2007 were collected from 37 and 41 hospitals, respectively, and from one commercial laboratory. Intermediate susceptibility was not included in the calculation of resistance rates. Results: Methicillin-resistant Staphylococcus aureus (MRSA) (64%), third-generation cephalosporin-resistant Klebsiella pneumoniae (29%), fluoroquinolone-resistant Escherichia coli (27%), Pseudomonas aeruginosa (33%), and Acinetobacter spp. (48%), and amikacin-resistant P. aeruginosa (19%) and Acinetobacter spp. (37%) were prevalent in hospitals in 2007. A gradual increase of vancomycin-resistant Enterococcus faecium and imipenem-resistant Acinetobacter spp. was observed. Higher incidences of third-generation cephalosporin-resistant E. coli and K. pneumoniae and imipenem-resistant P. aeruginosa were found in the commercial laboratory than in the hospitals. Conclusion: Methicillin-resistant S. aureus, third-generation cephalosporin-resistant K. pneumoniae, and fluoroquinolone-resistant E. coli, P. aeruginosa and Acinetobacter spp. remain prevalent in Korea, while the incidence of vancomycin-resistant E. faecium and imipenem-resistant Acinetobacter spp. has increased gradually. The higher prevalences of third-generation cephalosporin-resistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa in the commercial laboratory are a new concern.
URI
http://hdl.handle.net/YU.REPOSITORY/23376http://dx.doi.org/10.3349/ymj.2010.51.6.901
ISSN
0513-5796
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의과대학 > 진단검사의학교실 > Articles
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