A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction

Title
A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction
Author(s)
김영조김현국[김현국]정명호[정명호]안영근[안영근]김종현[김종현]채성철[채성철]허승호[허승호]성인환[성인환]장양수[장양수]라승운[라승운]배장호[배장호]조정관[조정관]박승정[박승정]
Keywords
ACUTE CORONARY SYNDROMES; PROGNOSTIC VALUE; REGISTRY; MORTALITY; TIROFIBAN; SPECTRUM; EVENTS; AGE
Issue Date
201012
Publisher
ELSEVIER IRELAND LTD
Citation
INTERNATIONAL JOURNAL OF CARDIOLOGY, v.145, no.3, pp.450 - 454
Abstract
Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short-and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 +/- 12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (>= 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/23220http://dx.doi.org/10.1016/j.ijcard.2009.06.001
ISSN
0167-5273
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의과대학 > 내과학교실 > Articles
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