Spitz naevus is rare in Korea

Title
Spitz naevus is rare in Korea
Author(s)
신동훈김유찬[김유찬]도정은[도정은]방동식[방동식]조백기[조백기]조광현[조광현]최정철[최정철]김문범[김문범]김명화[김명화]김시용[김시용]김수남[김수남]이증훈[이증훈]이석종[이석종]신정현[신정현]손숙자[손숙자]서기석[서기석]윤태영[윤태영]박찬금[박찬금]
Keywords
MALIGNANT-MELANOMA; CUTANEOUS MELANOMA; AGE; CHILDREN; SPINDLE; CANCER; ADULTS
Issue Date
201003
Publisher
WILEY-BLACKWELL PUBLISHING, INC
Citation
CLINICAL AND EXPERIMENTAL DERMATOLOGY, v.35, no.2, pp.135 - 139
Abstract
Background. Spitz naevi have not been widely studied in Asians. Aim. To compare the epidemiology and clinicopathological features of Spitz naevi in Koreans with lesions in western countries. Methods. In total, 80 Spitz naevi in 77 patients diagnosed over 10 years at 17 university hospitals in Korea were analysed. Results. The relative incidence of Spitz naevus vs. MM was 1 vs. 10.9. In most patients (75%) the Spitz naevi had been present for > 6 months. The size of the lesion was relatively large. Histologically, most of the lesions (54%) were the dermal type and pigmentation was common (49% of lesions). Immunohistochemical study found that all of the 34 lesions were positive for S-100 protein but only 14 (47%) were positive for HMB-45. Conclusion. Spitz naevus is rare in Korea. The lesions were more commonly larger, pigmented, and of the dermal type than reported in western countries.
URI
http://hdl.handle.net/YU.REPOSITORY/22762http://dx.doi.org/10.1111/j.1365-2230.2009.03401.x
ISSN
0307-6938
Appears in Collections:
의과대학 > 피부과학교실 > Articles
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