Gukulenins A and B, Cytotoxic Tetraterpenoids from the Marine Sponge Phorbas gukulensis

Title
Gukulenins A and B, Cytotoxic Tetraterpenoids from the Marine Sponge Phorbas gukulensis
Author(s)
최혁재Su Young Park[Su Young Park]Hoosang Hwang[Hoosang Hwang]Heonjoong Kang [Heonjoong Kang ]Jung-Rae Rho[Jung-Rae Rho]
Keywords
NATURAL-PRODUCTS; MACROLIDES
Issue Date
201004
Publisher
AMER CHEMICAL SOC
Citation
JOURNAL OF NATURAL PRODUCTS, v.73, no.4, pp.734 - 737
Abstract
Gukulenins A (1) and B (2), both having an unprecedented skeleton with a bis-tropolone moiety, were isolated from the Korean marine sponge Phorbas gukulensis. They exhibited significant cytotoxicity against human pharynx, stomach, colon, and renal cancer cell lines in the range 0.05-0.80 mu M.
URI
http://hdl.handle.net/YU.REPOSITORY/22593http://dx.doi.org/10.1021/np900606h
ISSN
0163-3864
Appears in Collections:
약학대학 > 약학부 > Articles
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