Corpus callosum injury in patients with diffuse axonal injury: A diffusion tensor imaging study

Title
Corpus callosum injury in patients with diffuse axonal injury: A diffusion tensor imaging study
Author(s)
장성호장민철[장민철]
Keywords
TRAUMATIC BRAIN-INJURY; WHITE-MATTER INJURY; CLOSED-HEAD TRAUMA; CORTICOSPINAL TRACT; MR; INTEGRITY; LESIONS; TRACTOGRAPHY; FEATURES; MODERATE
Issue Date
201006
Publisher
IOS PRESS
Citation
NEUROREHABILITATION, v.26, no.4, pp.339 - 345
Abstract
Little is known about diffusion tensor image (DTI) findings of corpus callosum (CC) injury in patients with diffuse axonal injury (DAI). In the present study, we investigated the presence and extent of CC injury in patients with DAI. Twenty patients with DAI and 20 age-and sex-matched normal healthy controls subjects were recruited. Patients were divided into two groups according to the presence of a CC lesion on conventional brain MRI, namely, the CC (+) group (8 patients) and the CC (-) group (12 patients). DTIs were acquired using a sensitivity-encoding head coil at 1.5 T. The CC was divided into six mid-sagittal segments: the genu, rostral midbody, anterior midbody, posterior midbody, isthmus, and splenium. Fractional anisotropies (FA) and apparent diffusion coefficients (ADCs) were measured. FA values of all CC segments in DAI patients were significantly lower than those of controls (p < 0.001); whereas ADC values were either similar or marginally higher. FA values of the six sagittal segments in the CC (-) and (+) groups were significantly lower than those of controls, and ADC values were slightly higher, or showed no change. CC lesions may be present in DAI patients, irrespective of detection on conventional brain MRI. The authors suggest the probability that in cases of corpus callosum injury, DTI can offer a powerful means of detecting DAI.
URI
http://hdl.handle.net/YU.REPOSITORY/22313http://dx.doi.org/10.3233/NRE-2010-0571
ISSN
1053-8135
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE